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Clotrimazole 1% Cream is an antifungal formulation which is prescribed for treatment of tinea cruris, cutaneous candidiasis, and vaginal yeast infections. Active compound used in its formulation has chemical formula C22H17ClN2 with molar mass of 344.837 g/mol. applied topically, this cream shows 90% of protein binding ability with elimination half life of 2 hours. Clotrimazole 1% Cream works by altering permeability of fungal cell wall and inhibiting individual growth of fungal cells.